Results 81 to 90 of about 312,992 (268)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Computers and the Teaching of the Technical Subject

open access: yesAdvances in Electrical and Electronic Engineering, 2004
The contribution deals with the use of computers in the technical subject teaching. It shows more common view on the possibilities of the computer use. It also shows that there is a lin to concrete conditions of the use of computers. So there is not only
Dasa Ticha, Petr Bores
doaj  

Application of 4D printing in dentistry: A narrative review [PDF]

open access: yesJournal of Advanced Periodontology and Implant Dentistry
4D printing is an innovative digital manufacturing technology that originated by adding a fourth dimension, i.e., time, to pre-existing 3D technology or additive manufacturing (AM).
Yeshwanth Perambudhuru   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Thermal Performance Analysis and Structural Optimization of Main Functional Components of Computers

open access: yesApplied Sciences
In today’s data-driven age, the thermal properties of computer transistors play an important role. In this research, finite element simulation is employed to construct the structural model of the primary components within a computer chassis, and the ...
Tengyue Pan   +9 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Optical Computing and Computational Complexity

open access: yes, 2006
This work concerns the computational complexity of a model of computation that is inspired by optical computers. The model is called the continuous space machine and operates in discrete timesteps over a number of two-dimensional images of fixed size and arbitrary spatial resolution.
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

THE ATTITUDES OF TEACHERS AND SPECIAL EDUCATORS TOWARDS THE USE OF COMPUTERS AND MODERN TECHNOLOGY IN TEACHING CHILDREN WITH DEVELOPMENTAL DISABILITIES

open access: yesResearch in Education and Rehabilitation
The goal of education is to provide favorable conditions for creativity, cooperation, actualization, and flexibility in order to prepare students for active work and functioning in society. This is especially important for inclusive education as students
Aleksandra Bašić   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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