Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
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Computing 10,000-Foot Pressures from Surface Data [PDF]
, 1945 Francis K. Davis, A. Klein
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Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
Design of Low-Cost and Highly Energy-Efficient Convolutional Neural Networks Based on Deterministic Encoding. [PDF]
Sensors (Basel)Tong T, He Q, Nie X, Zhao Y.
europepmc +1 more source
An easie demonstration of the analogy of the logarithmick tangents to the meridian line or sum of the secants: with various methods for computing the same to the utmost exactness, by E. Halley [PDF]
Edmond Halley
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Further notes on the Position of the Sun's Axis of Rotation, as deduced from observations by C. H. F. Peters in the years 1860-1870. Papers of the I.U.S.R. Computing Bureau. No. IV [PDF]
, 1909 H. H. Turner
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