Results 251 to 260 of about 4,892,723 (368)

Automatic Computing Machinery [PDF]

, 1950

openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Fast noisy long read alignment with multi-level parallelism. [PDF]

BMC Bioinformatics
Xia Z, Yang C, Peng C, Guo Y, Guo Y, Tang T, Cui Y.   +6 more
europepmc   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Photon-efficient camera with in-sensor computing. [PDF]

Nat Commun
Guan Y, Li H, Zhang Y, Qiu Y, Zhang L, Ji X, Wang H, Chen Q, Ma L, Wang X, Yang Z, Tu X, Zhao Q, Jia X, Chen J, Kang L, Wu P.   +16 more
europepmc   +1 more source

On tables for setting out the width of cuttings and embankments on sidelong ground; and also forrnulæ for computing thearea of vertical section [PDF]

R Clark
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Discussion: “A Mechanical Analyzer for Computing Transient Stresses in Airplane Structures” (Bisplinghoff, R. L., Pian, T. H. H., and Levy, L. I., 1950, ASME J. Appl. Mech., 17, pp. 310–314) [PDF]

, 1951
Robert H. Scanlan
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Sustainability in construction economics as a barrier to cloud computing adoption in small-scale Building projects. [PDF]

Sci Rep
Zonghui W, Veniaminovna KO, Vladimirovna VO, Ivan K, Isleem HF.   +4 more
europepmc   +1 more source

Distributed Computing – Grid Computing: Self-Organising Grid Resource Management [PDF]

, 2006
Lazarevic, A.
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