Results 261 to 270 of about 4,892,723 (368)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Correction: Learning the therapeutic targets of acute myeloid leukemia through multiscale human interactome network and community analysis. [PDF]

BioData Min
Sivanathan S, Hu T.
europepmc   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Future scientific paradigms in the integration of materials, aerospace and information. [PDF]

Natl Sci Rev
Wang C, Zhao Y, Hu S, Jia H, Yan W, Fan D, Cheng Y, Bao W, Wang Z, Yuan L, Yan F, Zhu M, Jiang C.   +12 more
europepmc   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Partial discharge defect recognition method of switchgear based on cloud-edge collaborative deep learning. [PDF]

Sci Rep
Jia Z, Fan S, Wang Z, Shao S, He D.
europepmc   +1 more source

I. Translation of a Letter from Professor Hansen to G. B. Airy, Esq. the Astronomer Royal, on a New Method of Computing the Perturbations of Planets, whose Eccentricities and Inclinations are not small. Communicated by G. B. Airy, Esq. [PDF]

openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Computer News

Canadian Journal of Learning and Technology / La revue canadienne de l’apprentissage et de la technologie, 1982
openaire   +13 more sources

Task Similarity-Aware Cooperative Computation Offloading and Resource Allocation for Reusable Tasks in Dense MEC Systems. [PDF]

Sensors (Basel)
Mu H, Wu S, He P, Chen J, Wu W.
europepmc   +1 more source