Results 51 to 60 of about 1,105,055 (318)

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yesFEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic   +2 more
wiley   +1 more source

Fundamental Limits in Dissipative Processes during Computation

open access: yesEntropy, 2019
An increasing amount of electric energy is consumed by computers as they progress in function and capabilities. All of it is dissipated in heat during the computing and communicating operations and we reached the point that further developments are ...
Davide Chiucchiú   +4 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Assessing the Effectiveness of Automated Emotion Recognition in Adults and Children for Clinical Investigation

open access: yesFrontiers in Human Neuroscience, 2020
Recent success stories in automated object or face recognition, partly fuelled by deep learning artificial neural network (ANN) architectures, have led to the advancement of biometric research platforms and, to some extent, the resurrection of Artificial
Maria Flynn   +6 more
doaj   +1 more source

Resource Allocation in Networking and Computing Systems: A Security and Dependability Perspective

open access: yesIEEE Access, 2023
In recent years, there has been a trend to integrate networking and computing systems, whose management is getting increasingly complex. Resource allocation is one of the crucial aspects of managing such systems and is affected by this increased ...
Md Muhidul I. Khan, Gianfranco Nencioni
doaj   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

On discovering functions in actin filament automata [PDF]

open access: yesRoyal Society Open Science, 2019
We simulate an actin filament as an automaton network. Every atom takes two or three states and updates its state, in discrete time, depending on a ratio of its neighbours in some selected state.
Andrew Adamatzky
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

DATA DRIVEN SMART CITIES: INTEGRATING THE POWER OF 5G COMPUTING [PDF]

open access: yesProceedings on Engineering Sciences
The fifth generation of mobile networks is going to transform the way we live, work, and communicate. The shift from 4G to 5G would be a crucial enabler for the growth of smart cities due to its superior speed and minimal latency.
Samarth Sharma   +2 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

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