Efficacy of four anti-vascular endothelial growth factor agents and laser treatment for retinopathy of prematurity: A network meta-analysis [PDF]
, 2023 This study undertakes a comprehensive comparison of five different interventions for the treatment of type-1 retinopathy of prematurity (ROP) and aggressive posterior ROP (APROP), offering insights into their relative efficacies and contributing to ...
Dong Zhou +6 more
core +2 more sources
Different approaches for treating myopic choroidal neovascularization: a network Meta-analysis [PDF]
, 2023 AIM: To evaluate the efficacy of intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF), photodynamic therapy (PDT), and laser treatment (LT) for anatomical and functional improvement in myopic choroidal neovascularization (mCNV ...
Hua Fan +4 more
core +1 more source
The Role of Intravitreal Anti-VEGF Agents in Rabbit Eye Model of Open-Globe Injury
Journal of Ophthalmology, 2021 Purpose. To evaluate the effects of intravitreal anti-VEGF agents in a rabbit model of open-globe injury (OGI). Methods. OGI was induced in the right eyes of 75 Belgian rabbits by making 5 mm circumferential incision placed 6 mm behind the limbus.
Xiao Zhao +10 more
doaj +1 more source
Optical coherence tomography angiography for macular microvessels in ischemic branch retinal vein occlusion treated with conbercept: predictive factors for the prognosis [PDF]
, 2023 AIM: To evaluate the predicative factors of visual prognosis using optical coherence tomography angiography (OCTA) in ischemic branch retinal vein occlusion (BRVO) patients with macular edema (ME) after anti-vascular endothelial growth factor (VEGF ...
Guang-Li Sun +4 more
core +1 more source
Ocular Therapeutics and Molecular Delivery Strategies for Neovascular Age-Related Macular Degeneration (nAMD) [PDF]
, 2021 Age-related macular degeneration (AMD) is the leading cause of vision loss in geriatric population. Intravitreal (IVT) injections are popular clinical option.
Dyawanapelly, Sathish +2 more
core +2 more sources
Clinical effect of conbercept on improving diabetic macular ischemia by OCT angiography [PDF]
BMC Ophthalmology, 2020 Abstract Background Varying degrees of macular ischemia generally occur in diabetic retinopathy (DR). This study aims to evaluate the effect of conbercept with 3+ pro re nata (PRN) on macular perfusion status in patients with diabetic macular edema (DME) and quantitatively assess changes in ...
Ziyi Zhu +6 more
openaire +3 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose Retinopathy of prematurity (ROP) is a major cause of childhood blindness, and selecting the optimal treatment between anti‐vascular endothelial growth factor (anti‐VEGF) and laser therapy is crucial. Understanding their impact on key outcomes, particularly mortality, is essential for informed clinical decision‐making.
Wei‐De Wang +10 more
wiley +1 more source
BMC Ophthalmology, 2017 Background To compare the efficacy of intravitreal conbercept and ranibizumab in the treatment of diabetic macular edema (DME) in a real-life clinical practice. Methods This was a retrospective study.
Yule Xu +4 more
doaj +1 more source
Advanced Science, Volume 13, Issue 1, 5 January 2026.Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen +12 more
wiley +1 more source
A hypothetical therapeutic effect of light peripheral panretinal photocoagulation in neovascular age-related macular degeneration [PDF]
, 2022 Background: Vascular endothelial growth factor (VEGF) is a significant modulator of ocular angiogenesis, including that of neovascular age-related macular degeneration (nAMD).
Mansour, Ahmad M +2 more
core +2 more sources