Results 91 to 100 of about 55,398 (324)
A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Advanced Science, EarlyView.Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
Thought experiments in current metaphilosophical debates [PDF]
, 2018 Although thought experiments were first discovered as a sui generis methodological tool by philosophers of science (most prominently by Ernst Mach), the tool can also be found – even more frequently – in contemporary philosophy.
Cohnitz, Daniel, Häggqvist, Sören
core
Advanced Science, EarlyView.By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
The Turing Test and the Zombie Argument [PDF]
, 2004 In this paper I shall try to put some implications concerning the Turing's test and the so-called Zombie arguments into the context of philosophy of mind.
Kostic, Daniel
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A Perspective on the Applications of Triphasic Gas Storage in Electrochemical Systems
Advanced Science, EarlyView.Gas storage in microporous materials positioned locally at an electrode or electrocatalyst surface enhances electrochemical processes. Abstract Microporous materials store gases under dry conditions (e.g., hydrogen or oxygen via physisorption), but in some cases microporous materials also show triphasic (e.g., in a solid|gas|liquid system) gas storage ...
Zhongkai Li +9 more
wiley +1 more source
The “Non-atheistic-thesis-of-Cartesian-metaphysics” [PDF]
, 2018 In support of Descartes’ epistemology, Lex Newman advances the ‘Non-atheistic-knowledge- thesis’, i.e., indefeasible knowledge cannot be gained unless the existence of God is proved.
González, Rodrigo Alfonso
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A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat
Advanced Science, EarlyView.An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su +10 more
wiley +1 more source
Grounding, conceivability, and the mind-body problem
Synthese, 2016 This paper challenges the soundness of the two-dimensional conceivability argument against the derivation of phenomenal truths from physical truths (cf. Chalmers in The conscious mind, Oxford University Press, Oxford, 1996; The character of consciousness,
Hasen Khudairi
semanticscholar +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
, 2005 This paper argues that there are true synthetic modal claims and that modal questions in philosophy are to be interpreted not in terms of logical necessity but in terms of synthetic necessity.
Wachter, Daniel von
core +1 more source