Results 201 to 210 of about 51,006 (322)

Phase I Metabolism of Novel Phencyclidine Derivative 3‐Cl‐PCP: In Vitro Studies With Pooled Human Liver Microsomes and Investigation of a Post‐Mortem Case

open access: yesDrug Testing and Analysis, EarlyView.
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler   +3 more
wiley   +1 more source

Does conceivability entail possibility?

open access: yesThe Reasoner, 2007
Clayton Littlejohn
doaj  

Dual‐Stabilized Single‐Site Fe(II) for Catalytic Conversion of CO2 to Propiolic Acid Under Ambient Condition

open access: yesEcoEnergy, EarlyView.
We develop a highly cost‐effective heterogeneous catalyst for efficient CO2 conversion to propiolic acid under mild conditions via a nano‐confined approach with porous MIL support. ABSTRACT Efficient conversion of carbon dioxide to organics has been a promising outlet for value‐added carbon dioxide consumption.
Bin Lei   +6 more
wiley   +1 more source

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad   +9 more
wiley   +1 more source

One‐Pot Gold(I)‐Catalyzed Rautenstrauch Rearrangement/Nitrosocarbonyl Hetero‐Diels–Alder Reaction Sequence for the Synthesis of α‐Hydroxylated Cyclopentenones

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The regio‐ and stereoselective synthesis of ring‐fused α‐hydroxy‐2‐cyclopentenones is achieved by a one‐pot gold(I)‐catalyzed Rautenstrauch rearrangement/nitrosocarbonyl hetero‐Diels–Alder reaction/ring opening sequence carried out on suitable propargyl esters followed by selective NO bond cleavage.
Dina Scarpi   +3 more
wiley   +1 more source

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