Results 31 to 40 of about 51,006 (322)

V-On Conceiving the Inconsistent [PDF]

open access: yesProceedings of the Aristotelian Society (Hardback), 2014
I present an approach to our conceiving absolute impossibilities—things which obtain at no possible world—in terms of ceteris paribus intentional operators: variably restricted quantifiers on possible and impossible worlds based on world similarity. The explicit content of a representation plays a role similar in some respects to the one of a ceteris ...
openaire   +3 more sources

Correct Conceivability and its Role in the Epistemology of Modality

open access: yes, 2020
The starting point of this paper is an argument to the conclusion that the definition of metaphysical possibility in terms of correct conceivability, conceivability informed by knowledge of relevant essences, found in Rosen (2006) is equivalent to a ...
R. Michels
semanticscholar   +1 more source

The obscurity of the physical: an objection to Chalmers’ conceivability argument

open access: yesFilosofia Unisinos, 2020
A zombie world is a possible world in which all the microphysical truths are identical to the truths in our world, but no one is phenomenally conscious.
Felipe G. A. Moreira
doaj   +1 more source

Materializm Typu-B i Treść Pojęć Fenomenalnych (Type-B Materialism and the Content of Phenomenal Concepts)

open access: yesAnaliza i Egzystencja, 2019
According to type-B materialism, the corresponding phenomenal and physical concepts are distinct concepts of the same properties. This view is very controversial because of the fact that phenomenal concepts, along with physical concepts, refer non ...
Karol Polcyn
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Scrutiny of the Two-Dimensional Argument against Physicalism

open access: yesPrincipia: An International Journal of Epistemology, 2023
Chalmers’s two-dimensional argument against materialism (aka the zombie argument) is arguably the most ingenious attempt to ground a view about fundamental reality on epistemic considerations.
Wilson Mendonça   +1 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Presentation

open access: yesFilosofia Unisinos, 2020
We are pleased to present to the Brazilian and international philosophical community the third number of the twenty-one volume (2020 - September-December) of Unisinos Journal of Philosophy, which consists of eight articles and one book review.
Denis Coitinho
doaj   +1 more source

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