Results 241 to 250 of about 506,115 (309)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Plasma emicizumab concentrations and bleeding rates in children and adults with severe hemophilia A. [PDF]

Res Pract Thromb Haemost
Teitel J, Carcao M, Sholzberg M, Thillaye-Kerr R, Swarup V, Markovic T, Bouskill V.   +6 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Intravenous thrombolysis in acute ischemic stroke after reversal of warfarin anticoagulation in patients with mechanical heart valve prostheses and an INR > 1.7. [PDF]

Front Neurol
Neumann J, Cernik D, Bilik J.
europepmc   +1 more source

Mango Peel Fermented with Ethanol-Industry Yeast Waste and Urea Modulates In Vitro Rumen Fermentation, Nutrient Degradability, and Methane Concentration. [PDF]

Animals (Basel)
Prachumchai R, Harakotr B, Somparn P, Suwannakaew M, Cherdthong A, Suntara C, Rawdkuen S.   +6 more
europepmc   +1 more source

A physiology-based approach to ROTEM interpretation for bleeding management in cardiac surgery: A narrative review. [PDF]

Saudi J Anaesth
Elsuhbi N, Tai A, Alnouri M, Alzahrani S.   +3 more
europepmc   +1 more source

Effects of 5-Hydroxymethylfurfural on In Vitro Rumen Fermentation Characteristics and Bacterial Community Structure of Diets with Different Concentrate-to-Roughage Ratios. [PDF]

Animals (Basel)
Du X, Ren N, Wang X, Qin J, Zhang W, He L.   +5 more
europepmc   +1 more source

Physicochemical and Microbiological Properties of Yoghurt Made Form Defatted Milk Mixtures and Concentrated Buttermilk Fortified with Herbal Extract. [PDF]

Foods
Tultabayeva T, Zhakupova G, Sagandyk A, Makangali K, Syzdykova A, Gajimuradova A, Muldasheva A, Dairova K.   +7 more
europepmc   +1 more source