Results 101 to 110 of about 1,281,063 (293)
Comparison and Analysis of Productivity Growth and R&D Investment in theElectrical Machinery Industries of the United States and Japan [PDF]
This paper presents a comparative analysis of productivity growth in the U.S. and Japanese electrical machinery industries in the postwar period. This industry has experienced rapid growth in output and productivity and high rates of capital formation in
Ingmar R. Prucha, M. Ishaq Nadiri
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Reducing Inequality And Poverty During Liberalisation In China: Rural And Agricultural Experiences And Policy Options [PDF]
While liberalisation is designed to help growth and alleviate poverty by removing impediments that stop people and regions from specialising and trading, the process known as Core liberalisation (CL) has three components: it frees markets in goods and ...
Michael Lipton, Qi Zhang
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
An evaluation of NASA's program in human factors research: Aircrew-vehicle system interaction [PDF]
Research in human factors in the aircraft cockpit and a proposed program augmentation were reviewed. The dramatic growth of microprocessor technology makes it entirely feasible to automate increasingly more functions in the aircraft cockpit; the promise ...
core +1 more source
The Economic Impact of IMF and World Bank Programs in the Middle East and North Africa: A Case Study of Jordan, Egypt, Morocco and Tunisia, 1983-2004 [PDF]
, 2010 This paper examines whether the economic reforms attached to IMF and World Bank policy-based lending in the Middle East and North Africa have stimulated sustained economic growth.
El-Said, Hamed, Harrigan, Jane
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Stuck Between Surplus and Shortage: Demand for Skills in the Russian Industry [PDF]
In order to remain competitive, firms need to keep the quantity and composition of jobs close to the optimal for their given output. Since the beginning of the transition period, Russian industrial firms have been widely reporting that the quantity and ...
A. Lukiyanova +2 more
core +3 more sources
Construction And Functional Verification Of Prevascularized Cgf/Gelma Composite Matrix
International Dental JournalAim or purpose: Vascularization is the key to tissue-engineered organoid construction. In this study, GelMA was used for the modification of concentrated growth factors (CGF), combined with acellular vascular matrix (ACVM)-0.25% human-like collagen I ...
Xuqian Liu, Minhai Nie, Qiuyue Mou
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source