Results 131 to 140 of about 1,281,063 (293)
INTEREST GROUPS, VETO POINTS AND ELECTRICITY INFRASTRUCTURE DEPLOYMENT [PDF]
In this paper we examine the effects of interest group pressure and the structure of political institutions on infrastructure deployment by state-owned electric utilities in a panel of 78 countries during the period 1970 – 1994.
Bennet A. Zelner, Witold J. Henisz
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Mortgage Foreclosures in Atlanta: Patterns and Policy Issues [PDF]
, 2005 Metropolitan Atlanta is experiencing a foreclosure boom as the number of failed mortgages more than doubled in less than five years, between 2000 and 2005.
Mark Duda, William C. Apgar
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Is it Easier to Escape from Low Pay in Urban Areas? Evidence from the UK [PDF]
, 2004 In this paper we compare periods of low pay employment between urban and rural areas in the UK. Using the British Household Panel Survey, we estimate the probability that a period of low pay employment will end allowing for a number of possible outcomes,
Centre for European Labour Market Research +3 more
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Working Futures 2017-2027 : Long-run labour market and skills projections headline report [PDF]
, 2020 This report provides a concise overview of Working Futures 2017-2027 results for the UK. It presents historical trends and future prospects by sector for the UK and its constituent nations and the English regions. The prime focus of Working Futures is on
Barnes, Sally-Anne +6 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Impact of Public Research Units on Regional Innovation Processes and Regional Economic Development [PDF]
It is well-known today that innovation activities of private firms play a significant role for economic growth in less-developed regions. There are many studies on these interrelations and on explaining how regional innovation processes are working and ...
Diana Roth, Martin T.W. Rosenfeld
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source