Results 211 to 220 of about 1,588,866 (313)

Biomechanical Applications of Finite Element Analysis in Orthodontics: A Scoping Review of Force Distribution, Tooth Movement, and Mechanical Performance. [PDF]

Dent J (Basel)
Antonio VJ, César GF, Héctor F, Verónica ZA, Carlos BJ, Carlos MT, Amaury PG.   +6 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Emergency Departments as Early Clinical Sentinels and the Final Operational Buffer. [PDF]

J Acute Med
Chi CH.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Toward Accurate Estimation of Extractable Organic Fluorine by Analysis of Fluoride Contamination in Extracts Using Gas Chromatography. [PDF]

Anal Chem
Kikuchi-McIntosh J, Montelius M, Sporre G, Bastviken D, Svensson T.   +4 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Unite against Malaria: challenges and achievements in malaria control around the globe. [PDF]

Nat Commun
europepmc   +1 more source

Towards a circular economy with application of salmon silage to a grassland in Chilean Patagonia. [PDF]

Sci Rep
Zamora D, Radic-Schilling S.
europepmc   +1 more source