Results 21 to 30 of about 27,463 (215)
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
The concentration–compactness principle for Orlicz spaces and applications
AbstractIn this paper, we extend the well‐known concentration–compactness principle of P.L. Lions to Orlicz spaces. As an application, we show an existence result to some critical elliptic problem with nonstandard growth.
Julián Fernández Bonder, Analía Silva
openaire +4 more sources
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Concentration-Compactness Principle for embedding into multiple exponential spaces [PDF]
Let Ω⊂Rn , n 2 , be a bounded domain and let α < n−1 . We prove the ConcentrationCompactness Principle for the embedding of the Orlicz-Sobolev space W 1 0 L n logn−1 L logα logL(Ω) into the Orlicz space corresponding to a Young function that behaves like exp(exp(t n n−1−α )) for large t .
openaire +1 more source
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
A simple derivation of BV bounds for inhomogeneous relaxation systems [PDF]
We consider relaxation systems of transport equations with heterogeneous source terms and with boundary conditions, which limits are scalar conservation laws. Classical bounds fail in this context and in particular BV estimates.
Perthame, Benoit +2 more
core +2 more sources
Blow-up Profile of Neutron Stars in the Chandrasekhar theory
We study the Chandrasekhar variational model for neutron stars, with or without an external potential. We prove the existence of minimizers when the attractive interaction strength $\tau$ is strictly smaller than the Chandrasekhar limit $\tau_c$ and ...
Nguyen, Dinh-Thi
core +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source

