Results 51 to 60 of about 115,512 (248)

Concentration-Compactness Principle for Moser-type Inequalities in Lorentz-Sobolev Spaces

open access: yesPotential Analysis, 2015
Let n ∈ 𝜖, n ≥ 2, q ∈ (1, ∞) and let ${\Omega }\subset \mathbb {R}^{n}$ be an open bounded set. We study the Concentration-Compactness Principle for the embedding of the Lorentz-Sobolev space
Li Dongliang, Zhu Maochun
openaire   +4 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

EXISTENCE OF STEADY STATES FOR THE MAXWELL–SCHRÖDINGER–POISSON SYSTEM: EXPLORING THE APPLICABILITY OF THE CONCENTRATION–COMPACTNESS PRINCIPLE [PDF]

open access: yesMathematical Models and Methods in Applied Sciences, 2013
This paper reviews recent results and open problems concerning the existence of steady states to the Maxwell–Schrödinger system. A combination of tools, proofs and results are presented in the framework of the concentration–compactness method.
Catto, Isabelle   +3 more
openaire   +6 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Concentration-compactness principle for nonlocal scalar field equations with critical growth

open access: yesJournal of Mathematical Analysis and Applications, 2017
The aim of this paper is to study a concentration-compactness principle for homogeneous fractional Sobolev space $\mathcal{D}^{s,2} (\mathbb{R}^N)$ for ...
João Marcos do Ó, Diego Ferraz
openaire   +3 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
NataĹĄa Stojanović GuĹžvić   +31 more
wiley   +1 more source

Uncertainty principle for the two-sided quaternion windowed linear canonical transform [PDF]

open access: yesarXiv, 2021
In this paper, we investigate the (two-sided) quaternion windowed linear canonical transform (QWLCT) and study the uncertainty principles associated with the QWLCT. Firstly, several important properties of the QWLCT such as bounded, shift, modulation, orthogonality relation, are presented based on the spectral representation of the quaternionic linear ...
arxiv  

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

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