Results 161 to 170 of about 491,712 (299)

Severe Hypoxia Reduces Adenylyl Cyclase 6 Expression and Function in Bronchial Epithelial Cells. [PDF]

FASEB Bioadv
Cunnington RH, Singh N, Shafizadeh M, Hanrahan JW, Dakshinamurti S, Chelikani P.   +5 more
europepmc   +1 more source

Intracellular control of renin release - an overview [PDF]

, 1986
Kurtz, Armin
core   +1 more source

Archaeological Damage Assessment in Conflict Zones: Integrating Satellite Imagery and Ground Surveys in Daraa, Syria

Archaeological Prospection, EarlyView.
ABSTRACT Satellite remote sensing is among the most significant modern methodologies supporting field archaeology. In addition to its efficiency in identifying archaeological sites, remote sensing offers a safe and cost‐effective approach in conflict zones.
Amal Al Kassem, Kristen Hopper, Ismael M. Ibraheem, Andreas Maier, Mohammad Khair Nassrallah, Jürgen Richter   +5 more
wiley   +1 more source

An inter-subunit path is required for entropically-driven and negatively cooperative binding of cyclic nucleotides in the HCN2 channel. [PDF]

Commun Biol
Costa F, Ng LCT, Chow SS, Van Petegem F, Accili EA.   +4 more
europepmc   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Protocol to identify the signaling network of nucleotide second messengers in Shigella sonnei. [PDF]

STAR Protoc
Cui B, Chen X, Wang M, Deng Y.
europepmc   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura B. Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore   +19 more
wiley   +1 more source

Light-activated cAMP signaling controls sodium-driven motility in <i>Vibrio cholerae</i>. [PDF]

Proc Natl Acad Sci U S A
Xu J, Nakamura S, Tomoyose S, Shimabuku R, Tomioka R, Yamashiro T.   +5 more
europepmc   +1 more source

ANK1 and EPB41 Variants and The Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, Accepted Article.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

From <i>Hydra</i> to Humans: Head Activator in Neurogenesis and Neurorepair. [PDF]

Cells
Klymenko A, Lutz D.
europepmc   +1 more source