Results 101 to 110 of about 179,097 (337)

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

open access: yesAdvanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu   +7 more
wiley   +1 more source

The Concentration Camps of the Anglo-Boer War. A Social History

open access: yesContree, 2013
No abstract available.
Randolph Vigne
doaj   +1 more source

Tapol bulletin no, 76, July 1986 [PDF]

open access: yes, 1987
Contents: Fretilin's map of the concentration camps -- IGGI bolsters a declining economy -- Arms sales: Battle of the giants -- The 'missing link' emerges again, by Professor Wertheim -- Sanusi goes on trial again -- Transmigration programme under attack

core  

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

open access: yesAdvanced Science, EarlyView.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan   +14 more
wiley   +1 more source

A tipificação do totalitarismo segundo Hannah Arendt

open access: yesDoisPontos, 2008
This essay presents an extract of a research concerning the relation between nature and politics, emphasizing the processes of naturalization threatening human life, as they are discussed in contemporary political philosophy.
Odilio Alves Aguiar
doaj  

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

“Representing Canadian Interests in all Matters Relative to Canadian War Dead:” Lt. Col. J.A. Bailie and the Recovery, Concentration and Burial of the “C” Force Casualties in Japan and Hong Kong [PDF]

open access: yes, 2018
: The processes and rituals of grieving, memorializing and remembering a nation’s war dead are well known, while the project of recovering, concentrating and preparing wartime casualties for burial is less clearly understood.
Sweeney, Mark
core   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

open access: yesAdvanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou   +14 more
wiley   +1 more source

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