Advanced Science, EarlyView.An Automated ex vivo culture system BaSIC, tailored for SCN slices and cell culture, which automates medium exchange and ensures a stable internal environment is developed. BaSIC enables real‐time observation of tissue/cell responses to diverse but programmed stimuli.
Kui Han +7 more
wiley +1 more source
Changes in the concentration of cAMP, fructose 2,6‐bisphosphate and related metabolites and enzymes in Saccharomyces cerevisiae during growth on glucose [PDF]
, 1987 Jean François +2 more
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Advanced Science, EarlyView.The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu +10 more
wiley +1 more source
Site-selective cAMP analogs at micromolar concentrations induce growth arrest and differentiation of acute promyelocytic, chronic myelocytic, and acute lymphocytic human leukemia cell lines [PDF]
, 1988 Giampaolo Tortora +6 more
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Advanced Science, EarlyView.Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
La polarité spatiale dans les textes testimoniaux : Antelme, Cayrol, Levi, Rousset
Études romanes de Brno, 2013 Every ideological movement has its distinctive spaces that are continuously invoked and described. Its vocabulary, connections and patterns of encoding are still used, too.
Joanna Teklik
doaj
“This Kind of Love”: Descriptions of Lesbian Behaviour in Nazi Concentration Camps [PDF]
, 2017 Claudia Schoppmann
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“Jungle law reigned among the prisoners”: the meaning of cannibalism in the testimonies of Nazi concentration camps’ survivors [PDF]
, 2023 Kobi Kabalek
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Hannah Arendt and the law and ethics of administration : bureaucratic evil, political thinking and reflective judgment [PDF]
, 2012 After the absurd terrorism and violence of the totalitarianism and bureaucratic administrative and legal systems of the 20th century it does not give any meaning to rationalize harm as meaningful evil that even though it is evil may have some importance ...
Rendtorff, Jacob Dahl
core
Advanced Science, EarlyView.Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian +5 more
wiley +1 more source