Results 131 to 140 of about 179,097 (337)

Living Through Rat Hell: The Lives and Escape Attempts of Soldiers at Libby Prison [PDF]

open access: yes, 2018
This paper examines the lives and experiences of the men who survived the horrors of the Confederate prisoner of war camp, Libby Prison. Located inside the Confederacy’s capital city, the camp housed captured Union officers from its establishment in 1862
Davis, Blake
core   +1 more source

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li   +7 more
wiley   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

open access: yesAdvanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang   +15 more
wiley   +1 more source

Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning

open access: yesAdvanced Science, EarlyView.
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao   +14 more
wiley   +1 more source

«Reprimere e detenere»: l’altra faccia del conservadurismo español

open access: yesDiacronie. Studi di Storia Contemporanea, 2010
Se la Spagna rappresenta oggi uno dei principali fari europei di irradiazione della democrazia, non si può dire lo stesso rispetto al suo passato. Tra gli anni Venti e gli anni Settanta del XX secolo, quest’area fu sorretta da regimi dittatoriali che ...
Matteo Tomasoni ha conseguito il titolo di dottore di ricerca in Storia presso l’Universidad de Valladolid (Spagna, 2014), con una tesi sul fascismo spagnolo. Già dottore magistrale in Storia d’Europa presso l’Università di Bologna (2008), negli ultimi anni ha svolto attività di ricerca tra Spagna, Italia e Germania e collabora con vari gruppi fra cui il SIdIF (Seminario Interuniversitario de Investigadores del Fascismo), e la rivista “Zibaldone. Estudios italianos” di cui è membro della redazione. I suoi interessi sono rivolti allo studio dell’evoluzione storica del fascismo e dei movimenti politici del periodo tra le due guerre mondiali, oltre allo studio di alcuni aspetti della Prima Guerra Mondiale.
doaj  

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

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