Results 141 to 150 of about 179,097 (337)

Impact of incarceration in Nazi concentration camps on multimorbidity of former prisoners. [PDF]

open access: yesNeuropsychiatr Dis Treat, 2015
Jablonski RK   +4 more
europepmc   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo   +12 more
wiley   +1 more source

12(S)‐Hydroxyeicosatetraenoic acid induces cAMP production via increasing intracellular calcium concentration [PDF]

open access: bronze, 2003
Go Hasegawa   +5 more
openalex   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

open access: yesAdvanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra   +23 more
wiley   +1 more source

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

open access: yesAdvanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu   +10 more
wiley   +1 more source

Сравнительный анализ этапов и методов осуществления геноцида армян в Османской империи и Руандийского геноцида

open access: yesBanber Arevelagitut'yan Instituti
In genocide studies, for a more comprehensive, objective study of genocide committed against victim groups, the method of comparative analysis is used, which allows to identify both similarities and features between different examples of this crime.
Armen Marukyan
doaj   +4 more sources

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