Results 231 to 240 of about 4,717,932 (275)

Brain-Derived Neurotrophic Factor and Heat Shock Protein-32: Potential Targets for Microglial Response to Glucose and Oxygen Manipulation. [PDF]

Mol Neurobiol
Mussa BM, Srivastava A, Bajbouj K, Shafarin J, Rajan R, Hisham A.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Scalable Multiparametric Characterization of Aptamer-Target Interactions. [PDF]

ACS Nano
Sulliger M, Peters M, Sottini A, Stuber A, Yang K, Nakatsuka N, Ortega Arroyo J, Quidant R.   +7 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Salivary oxytocin responses to infant stimuli vary by EPDS scores among postpartum Japanese mothers without clinically diagnosed postpartum depression. [PDF]

Front Endocrinol (Lausanne)
Minami K, Higashida H, Yokoyama S, Tsuji T, Kagami N, Tsuji C.   +5 more
europepmc   +1 more source

Prospective Characterization Factors for Assessing Climate Change Impacts in Life Cycle Assessments. [PDF]

Environ Sci Technol
Barbosa Watanabe MD, Cherubini F.
europepmc   +1 more source

Enhanced Numerical Modeling of Non-Newtonian Particle-Laden Flows: Insights from the Carreau-Yasuda Model in Circular Tubes. [PDF]

Polymers (Basel)
Amangeldi M, Wei D, Perveen A, Zhang D.
europepmc   +1 more source

Temporal Change Rate in Sound Velocity Caused by Ultrasonic Heating for Evaluation of Steatotic Liver. [PDF]

Biology (Basel)
Itsubo M, Kobayashi Y, Yamamoto M, Takayanagi S, Akiyama I.   +4 more
europepmc   +1 more source

Organic Compounds as a Natural Alternative for Pest Control: How Will Climate Change Affect Their Effectiveness? [PDF]

Plants (Basel)
Usseglio VL, Zunino MP, Brito VD, Beato M, Theumer MG, Dambolena JS.   +5 more
europepmc   +1 more source