Results 101 to 110 of about 4,640 (267)

On existence and concentration of solutions to a class of quasilinear problems involving the 1-Laplace operator

open access: yes, 2017
In this work we use variational methods to prove results on existence and concentration of solutions to a problem in RN involving the 1-Laplacian operator.
Pimenta, Marcos T. O. [UNESP]   +4 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Multiple Solutions of a Nonlocal Problem with Nonlinear Boundary Conditions

open access: yesDiscrete Dynamics in Nature and Society
In this article, we consider a class of nonlocal p(x)-Laplace equations with nonlinear boundary conditions. When the nonlinear boundary involves critical exponents, using the concentration compactness principle, mountain pass lemma, and fountain theorem,
Jie Liu, Qing Miao
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The concentration-compactness principle for Musielak-Orlicz spaces and applications

open access: yes
This paper extends the Concentration-Compactness Principle to Musielak-Orlicz spaces, working in both bounded and unbounded domains. We show that our results include important special cases like classical Orlicz spaces, variable exponent spaces, double phase spaces, and a new type of double phase problem where the exponents depend on the solution ...
Bahrouni, Ala Eddine, Bahrouni, Anouar
openaire   +2 more sources

Concentration-compactness principle and applications to nonlocal elliptic problems

open access: yes, 2016
The main goal of this work is to analyze concentration-compactness principles for fractional Sobolev spaces based on the concentration compactness principle of P.-L. Lions and in the pro le decomposition for weak convergence in Hilbert spaces due to K.
Souza, Diego Ferraz de
core  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Strongly interacting bumps for the schrodinger-newton equations

open access: yes, 2009
We study concentrated bound states of the Schrodinger-Newton equations Moroz, Penrose and Tod proved the existence and uniqueness of ground states.
Winter, M, Wei, J
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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