Results 151 to 160 of about 2,426,264 (355)

The Balassa Index meets the Theil Index - a Decomposition Methodology for Location Studies [PDF]

open access: yes
This paper focuses on the decomposition of location measures according to a twofold geographical level of analysis. The methodology, based on the use of the Theil dissimilarity index, is potentially applicable to the assessment of the spatial ...
Eleonora Cutrini
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Investigation of Geographical and Socioeconomic Inequalities in Mortality from Road Traffic Accidents in Corpses Referred to Legal Medicine Organization of Iran

open access: yesمجله اپیدمیولوژی ایران, 2019
Background and Objectives: This research was conducted to investigate the socioeconomic and geographical inequality in mortality from road traffic accidents in Iran in 2016.
F Shahbazi   +4 more
doaj  

Inequality in benefit distribution of reducing the outpatient cost-sharing: evidence from the outpatient pooling scheme in China

open access: yesFrontiers in Public Health
ObjectiveThe implementation of the outpatient pooling scheme in China has substantially elevated the compensation levels for outpatient expenses. This study aims to assess whether socioeconomically disadvantaged enrollees benefit proportionally compared ...
Tao Zhang, Minyan Chen
doaj   +1 more source

Measurement and explanation of socioeconomic inequality in health with longitudinal data [PDF]

open access: yes
This paper presents a method for the measurement of changes in health inequality and income-related health inequality over time in a population. For pure health inequality (as measured by the Gini coefficient) and income-related health inequality (as ...
Andrew M. Jones, Ángel López
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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