The Geographic Concentration of Population and Income in Europe: Results for the Period 1984-1999 [PDF]
In this paper we use the Gini index to analyze the spatial concentration of income and population across European Union regions over the period 1984-1999.
Andrés FaÃña +2 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Synovial fluid concentrations of the C-propeptide of type II collagen correlate with body mass index in primary knee osteoarthritis [PDF]
, 1997 T. Kobayashi +6 more
openalex +1 more source
The current state and dynamics of regional disparities in Romania [PDF]
The paper aims to highlight the dynamics and current state of regional disparities in Romania, discussing both inter-regional disparities -between the eight development regions, corresponding to the NUTS II level- and intra-regional disparities -between ...
Bogdan Ileanu +3 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A method for measuring spatial effects on socioeconomic inequalities using the concentration index. [PDF]
Int J Equity Health, 2020 Kim SW +4 more
europepmc +1 more source
Association between oropharyngeal ph-monitoring, pepsin saliva concentration and degree of apnea–hypopnea index of obstructive sleep apnea [PDF]
, 2023 François Bobin, Jérôme R. Lechien
openalex +1 more source
Geographic Concentration in U.S. Manufacturing Industries: A Dartboard Approach [PDF]
This paper discusses the prevalence of Silicon Valley-style localizations of individual manufacturing industries in the United States. Several models in which firms choose locations by throwing darts at a map are used to test whether the degree of ...
Edward L. Glaeser, Glenn Ellison
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source