Results 161 to 170 of about 460,018 (294)

Adaptable Covalent Organic Framework‐Hydrogel Microneedles for Glucose‐Responsive Isoliquiritigenin Delivery in Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou, Zongjie Hu, Xiuwen Li, Huaman Geng, Yang Liu, Yajie Wang, Yunshu Yang, Guangdong Zhou, Yujie Hua, Di Wang   +9 more
wiley   +1 more source

Paleo-salt water dominates coastal aquifer salinization: A continental-scale study in China. [PDF]

Sci Adv
Zheng T, Guo B, Chang Q, Sun Q, Chen X, Zheng X, Wu J, Zheng Z, Gao S, Zheng C, Liu J, Wang D, Liu T, Liu X, Chen G, Xu X, Zhang B, Zhang L, Wu Y, Kolditz O, Luo J, Guadagnini A.   +21 more
europepmc   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Effects of Green Tea Extract and (+)-Catechin Hydrate on Sperm Quality and Seminal Plasma Antioxidant Activity: An In Vitro Study in Rams. [PDF]

Vet Med Sci
Nabhani R, Vakili ST, Mirzadeh K.
europepmc   +1 more source

Engineered AuNPs/fMWCNT Nanocomposite Electrodes for High‐Sensitivity Methylglyoxal Sensing in Saliva and Sweat for Non‐Invasive Diabetes Monitoring

Advanced Healthcare Materials, EarlyView.
An AuNPs/fMWCNT nanocomposite‐modified screen‐printed carbon electrode was engineered via sequential electrodeposition and integrated into a 3D‐printed microfluidic platform for ultrasensitive methylglyoxal detection. The non‐invasive sensing platform enables rapid analysis in saliva and sweat, highlighting strong potential for wearable point‐of‐care ...
Ahadul Amin Soshi, Md Younus Ali, Dadbeh Pazuki, Matiar M.R. Howlader   +3 more
wiley   +1 more source

OECD imports : diversification of suppliers and quality search [PDF]

This paper explores the evolution of OECD imports over time, measuring their concentration across origin countries at the product level. The authors find evidence of diversification followed, in the very last years of the sample period (post-2000), by a ...
Strauss-Kahn, Vanessa, Cadot, Olivier, Carrere, Celine   +2 more
core  

Pressure Modulation of Fluidic Patterns Inside the Nanochannel for Two States of Ionic Conductance. [PDF]

Micromachines (Basel)
Li X, Zhang X, Liu Y, Cao Z, Zhu X, Ye Z.   +5 more
europepmc   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Fish Introductions Reshape Antipredator Sensitivity in <i>Rana temporaria</i> Tadpoles Across Alpine Lakes. [PDF]

Ecol Evol
Mattioli G, Mangiacotti M, Vitaloni D, Balestrieri A, Sacchi R, Tiberti R, Bello L, Pellitteri-Rosa D, Gazzola A.   +8 more
europepmc   +1 more source

Predicting NOM (Natural Organic Matter) concentration in a drinking water resource: Lake Mälaren

Natural Organic Matter (NOM) poses increasing challenges for drinking water management, particularly in lakes impacted by both climate variability and land-use change. This study investigates NOM dynamics in lake Mälaren, Sweden, by analysing long-term trends in Total Organic Carbon (TOC), absorbance at 420 nm, and colour, across inflowing rivers and ...
openaire   +1 more source