Results 61 to 70 of about 3,250,523 (299)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Concentration polarization in nanochannel DNA electrophoresis [PDF]
, 2011 We demonstrate that the large field electrophoresis of a single DNA molecule in nanofluidic systems is accompanied by concentration polarization. We illustrate this phenomena by utilizing our electrophoretic simulation tool SIMUL. First we in-vestigate a
Das, Siddhartha +3 more
core
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Mass Transfer Coefficient in Multi-Stage Reformer/Membrane Modules for Hydrogen Production
Membranes, 2018 Hydrogen is a promising energy carrier, and is exploitable to extract energy from fossil fuels, biomasses, and intermittent renewable energy sources and its generation from fossil fuels, with CO2 separation at the source being one of the most promising ...
Diego Barba +4 more
doaj +1 more source
Velocity and Polarization of the microdroplets with different ion concentration.
, 2015 Velocity and Polarization of the microdroplets with different ion concentration.
Shizhu Wen (604356) +3 more
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Effect of salt concentration on permeation performance in hollow fiber type PRO membrane module
Mechanical Engineering Journal, 2017 The new sustainable power generation technique which can convert the salinity gradient energy to the hydroelectric energy is expected. This technique is called Pressure Retarded Osmosis (PRO).
Shingo TERASHIMA +5 more
doaj +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
A Hybrid CFD Platform for Colloidal Fouling Prediction in Electrodialysis
MembranesFouling phenomena are among the main issues in membrane processes, worsening unit performance and membrane properties. So far, few modelling approaches have been proposed to predict colloidal fouling in electromembrane-based technologies.
Francesco Volpe +4 more
doaj +1 more source
Heat and Mass Transport in Modeling Membrane Distillation Configurations: A Review
Frontiers in Energy Research, 2018 Identification and mitigation of challenges associated with membrane distillation (MD) modeling are very crucial to the applicability of MD technology in the industry. Several research studies have been carried out on direct contact membrane distillation
Samuel O. Olatunji, Lucy Mar Camacho
doaj +1 more source