Results 221 to 230 of about 9,618,149 (357)

Bridging the human-AI knowledge gap through concept discovery and transfer in AlphaZero. [PDF]

Proc Natl Acad Sci U S A
Schut L, Tomašev N, McGrath T, Hassabis D, Paquet U, Kim B.   +5 more
europepmc   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Concepts

, 2018
openaire   +1 more source

Conceptualizing resilience in public health: a philosophical approach. [PDF]

Philos Ethics Humanit Med
K JP, Ramanathan M.
europepmc   +1 more source

CELLULAR REACTIONS TO A DYE-PROTEIN WITH A CONCEPT OF THE MECHANISM OF ANTIBODY FORMATION [PDF]

, 1939
Florence Sabin
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

A concept-based interpretable model for the diagnosis of choroid neoplasias using multimodal data. [PDF]

Nat Commun
Wu Y, Liu Y, Yang Y, Yao MS, Yang W, Shi X, Yang L, Li D, Liu Y, Yin S, Lei C, Zhang M, Gee JC, Yang X, Wei W, Gu S.   +15 more
europepmc   +1 more source

The thermodynamic basis for the mineral facies concept [PDF]

, 1955
James B. Thompson
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Social Determinants of Suicide and Suicidality in Serving Military Personnel: A Global Scoping Review. [PDF]

Health Promot J Austr
Dawes NG, Topp SM, Fullagar BJ, Selman J, Pak A, Devine SG.   +5 more
europepmc   +1 more source