Results 161 to 170 of about 22,041,249 (385)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Design of a radiator shade for testing in a simulated lunar environment [PDF]

open access: yes
The National Aeronautics and Space Administration (NASA) and The Universities Space Research Association (USRA) have chosen the parabolic/catenary concept from their sponsored Fall 1991 lunar radiation shade project for further testing and development ...
Huff, Jaimi   +2 more
core   +1 more source

Creation of Alloy Design Concept for Anti Air-Born Salinity Weathering Steel

open access: diamond, 2000
Hiroshi Kihira   +5 more
openalex   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The ClaudicatioNet concept: design of a national integrated care network providing active and healthy aging for patients with intermittent claudication

open access: yesVascular Health and Risk Management, 2012
Gert-Jan Lauret,1,2 Harm JH Gijsbers,3 Erik JM Hendriks,2 Marie-Louise Bartelink,4 Rob A de Bie,2 Joep AW Teijink1,2 On behalf of the ClaudicatioNet Study Group members1Department of Vascular Surgery, Catharina Hospital, Eindhoven, The Netherlands ...
Lauret GJ   +5 more
doaj  

Pengembangan Konsep Landasan Robot Beroda Omnidirection Pemindah Barang Berbahan Extrusi Profil Aluminium

open access: yesJTRM
Penelitian ini mengkaji bagaimana pengembangan konsep dilakukan untuk merancang sebuah landasan robot beroda omnidirection berbahan ekstrusi profil aluminium yang digunakan untuk pemindah barang.
Ade Ramdan   +4 more
doaj   +1 more source

Water-responsive shape memory hybrid: Design concept and demonstration

open access: diamond, 2011
K. Fan   +7 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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