Results 201 to 210 of about 22,041,249 (385)

Product concept design method for improving user satisfaction based on case-based reasoning. [PDF]

Sci Rep
Cheng FM, Niu XJ, Zhou X, Chen C, Dong W, Hu GR, Chen N, Liu Z.   +7 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Application of formal optimization techniques in thermal/structural design of a heat-pipe-cooled panel for a hypersonic vehicle [PDF]

Nonlinear mathematical programming methods are used to design a radiantly cooled and heat-pipe-cooled panel for a Mach 6.7 transport. The cooled portion of the panel is a hybrid heat-pipe/actively cooled design which uses heat pipes to transport the ...
Camarda, Charles J., Riley, Michael F.
core   +1 more source

Design: “Yes” in “No”-Discussion on Enlightenment and Application of Ecological Design Concept to Artistic Design Practice

, 2014
Shuyun Rong
openalex   +1 more source

Inquiry-Based Experimental Design for Enhancement of Teaching and Learning of Chemistry Concepts

, 2022
Jean de Dieu Kwitonda, Aimable Sibomana, Emmanuel Gakuba, Claude Karegeya   +3 more
openalex   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Utilising Flash Meeting software in collaborative design-learning

, 2008
In this paper, we describe a case study of computer-supported collaborative learning in design using FM (FlashMeeting), a Web-based video-conferencing tool offered freely on OpenLearn. This 6-week experiment, involving Open University students and staff,
Ferreira, Giselle, Garner, Steven, Schadewitz, Nicole   +2 more
core  

A Study on Fashion Design Expression Characteristics applied to the concept of the Fold and Ecological Aesthetics [PDF]

, 2016
Jungmin Bae
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Mapping the low-tech concept: guiding design towards sustainable technologies

, 2022
Antoine Martin, Alexandre Gaultier, Clément Colin   +2 more
openalex   +1 more source