Results 221 to 230 of about 22,041,249 (385)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Inherent Safety Fast Reactor Concept of KAMADO-FR2 Design of Ultra-long Life Core and Reuse of LWR Spent Fuels

Tetsuo Matsumura, Takanori Kameyama
openalex   +1 more source

O DESIGN ASSOCIADO AO CONCEPT ART NO DESENVOLVIMENTO DE PERSONAGENS: UM ESTUDO DE CASO [PDF]

, 2014
Douglas Daniel Pereira, Milton Koji Nakata, Galdenoro Botura   +2 more
openalex   +1 more source

The concept of digital twins for tech operator training simulator design for mining and processing industry [PDF]

, 2020
И. И. Белоглазов, P. A. Petrov, V. Yu. Bazhin   +2 more
openalex   +1 more source

Concept Design for a 1-Lead Wearable/Implantable ECG Front-End: Power Management. [PDF]

Sensors (Basel), 2015
George L, Gargiulo GD, Lehmann T, Hamilton TJ.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The concept of a method basing on engineering knowledge and experience for adding the process of module manipulators design [PDF]

, 2018
Piotr Ociepka, Krzysztof Herbuś
openalex   +1 more source

A Modular Design Concept for Shaping Future Wireless TSN Solutions [PDF]

, 2020
Christoph Fischer, Dennis Krummacker, Michael Karrenbauer, Hans D. Schotten   +3 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source