Results 61 to 70 of about 3,595,676 (296)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk   +10 more
wiley   +1 more source

Accurate detecting concept drift in evolving data streams

open access: yesICT Express, 2020
Predictive models operating on the evolving data streams are dynamic. The performance of a model will deteriorate eventually when it suffers the effect of concept drift.
Myuu Myuu Wai Yan
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

A Classification and Novel Class Detection Algorithm for Concept Drift Data Stream Based on the Cohesiveness and Separation Index of Mahalanobis Distance

open access: yesJournal of Electrical and Computer Engineering, 2020
Data stream mining has become a research hotspot in data mining and has attracted the attention of many scholars. However, the traditional data stream mining technology still has some problems to be solved in dealing with concept drift and concept ...
Xiangjun Li   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Multi-type concept drift detection under a dual-layer variable sliding window in frequent pattern mining with cloud computing

open access: yesJournal of Cloud Computing: Advances, Systems and Applications
The detection of different types of concept drift has wide applications in the fields of cloud computing and security information detection. Concept drift detection can indeed assist in promptly identifying instances where model performance deteriorates ...
Jing Chen   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An Experimental Analysis of Drift Detection Methods on Multi-Class Imbalanced Data Streams

open access: yesApplied Sciences, 2022
The performance of machine learning models diminishes while predicting the Remaining Useful Life (RUL) of the equipment or fault prediction due to the issue of concept drift.
Abdul Sattar Palli   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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