Results 171 to 180 of about 7,783,300 (285)
The role of self-assessment in the formation of communication style in middle school children. [PDF]
Front PsycholAlimbayeva S +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Rethinking ossification of the posterior longitudinal ligament: Instability as the root, stabilization as the remedy. [PDF]
J Craniovertebr Junction SpineGoel A.
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
α-Synuclein burden amplification in Parkinson's disease: a unified genetic, molecular, and cellular framework. [PDF]
Front NeurolNoda S, Hattori N.
europepmc +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Calcium-based biomineralisation remodels the pathogen-host interface. [PDF]
Clin Transl MedFu L +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Revisiting bone healing strategies: the potential of reverse dynamization in veterinary orthopedics. [PDF]
Front Vet SciDatoussaid A, Balligand M, Picavet PP.
europepmc +1 more source