Results 231 to 240 of about 11,719,816 (381)

The freedom to forget. [PDF]

Dialogues Hum Geogr
Hepach MG.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Steering Amine-CO₂ Chemistry: A Molecular Insight into the Amino Site Relationship of Carbamate and Protonated Amine. [PDF]

ACS Omega
Nguyen TD, Chen X, Sharma R.
europepmc   +1 more source

Theoretical Aspects of the Formation of the Concept of Eurasian Security

K. Yu. Meleshin, A. B. Feonichev
openalex   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Bone grafts and synthetic substitutes in dental applications: a comprehensive review of molecular mechanisms, materials evolution, and clinical perspective. [PDF]

Front Bioeng Biotechnol
Wang H, Kang J.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A systematic review on the effect of individual characteristics and management practices on equine cognition. [PDF]

Anim Cogn
Ricci-Bonot C, Brosche K, Baragli P, Nicol C.   +3 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

(Re)Considering the jump scare in four elements. [PDF]

Front Psychol
Acosta EAM, Sears DRW.
europepmc   +1 more source