Results 141 to 150 of about 4,288,649 (289)

Desenvolvimento de conceitos: o paradigma das descobertas

Psicologia Escolar e Educacional
Keil investigou se a descoberta de essências internas ou princípios causais subjacentes alterariam as categorizações de crianças sobre conceitos de espécies naturais e artefatos. Esse trabalho replica parte do experimento de Keil (1989), buscando validar
José Fernando Bitencourt Lomônaco, Alessandra Gotuzo Seabra Capovilla, Carlos Eduardo Costa, Jussara Martins Albernaz, Marcia Azevedo De Souza, Ramatis Monteiro Aguiar   +5 more
doaj  

Using Queer Theory to Advance Understandings of 'Queer Caregiving' With LGBTQ+ Older Adults. [PDF]

Scand J Caring Sci
Hall S, Oswald A.
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Enhancing learning outcomes through post-discussion homework: the role of collaboration and task type. [PDF]

Front Psychol
Cheng X, Yuan R, Zhang Q, Zhai C.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Hope into Achievement: A Longitudinal Examination of Hope, Psychosocial Perceptions, and Academic Achievement in a Sample of High School Students. [PDF]

Behav Sci (Basel)
Dixson DD, Gentzis EA, Jansen L, Whitley K.   +3 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Mindfulness and academic engagement among medical students: the roles of psychological capital and self-concept clarity. [PDF]

BMC Psychol
Aldbyani A, Alhimaidi A, Chuanxia Z, Leng J, Alhadoor Z.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Summation, Saliency, and Saturation (3S): a continuum for a practical approach to assessing sample adequacy and analytic completeness in qualitative implementation research. [PDF]

Implement Sci Commun
Chepp V, Skoczylas M, Gray C.
europepmc   +1 more source