Results 51 to 60 of about 4,288,649 (289)
The Psychological Concept of Overcoming: Theory, Methods, and Diagnostics
Introduction. This paper (a) provides an overview of various theoretical and methodological approaches to studying the concept of ‘overcoming’, (b) presents terminological, semantic, and functional approaches to the analysis of the concept of ‘overcoming’
Виталий В. Андреев +1 more
doaj +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
This work presents the concept of kernel mean embedding and kernel probabilistic programming in the context of stochastic systems. We propose formulations to represent, compare, and propagate uncertainties for fairly general stochastic dynamics in a ...
Diehl, Moritz +3 more
core +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
An Interdisciplinary Concept of Activity
It is suggested that if Cultural-Historical Activity Theory (CHAT) is to fulfil its potential as an approach to cultural and historical science in general, then an interdisciplinary concept of activity is needed.
Andy Blunden
doaj
The Symmetrical Immune Network Theory and a New HIV Vaccine Concept [PDF]
The symmetrical immune network theory is based on Jerne’s network hypothesis. An improved version of the theory is presented. The theory is characterized by symmetrical stimulatory, inhibitory and killing interactions between idiotypic and ...
Geoffrey W. Hoffmann
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
<p>This paper attempts to discuss the importance, relevance and validity of the concept of equivalence as a constitutive notion in translation theory.
Bolaños Cuéllar Sergio
doaj
Multidimensional item response theory and the Force Concept Inventory
Research on the test structure of the Force Concept Inventory (FCI) has largely been performed with exploratory methods such as factor analysis and cluster analysis.
John Stewart +3 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source

