Results 61 to 70 of about 4,288,649 (289)
Towards a Theory Grounded Theory of Language [PDF]
In this paper, we build upon the idea of theory grounding and propose one specific form of theory grounding, a theory of language. Theory grounding is the idea that we can imbue our embodied artificially intelligent systems with theories by modeling the ...
Kosolapov, Oleksandr V. +3 more
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Interpreting the Quantum Wave Function in Terms of 'Interacting Faculties' [PDF]
In this article we discuss the problem of finding an interpretation of quantum mechanics which provides an objective account of physical reality. In the first place we discuss the problem of interpretation and analyze the importance of such an objective ...
de Ronde, Christian
core +1 more source
On (non-Hermitian) Lagrangeans in (particle) physics and their dynamical generation
On the basis of a new method to derive the effective action the nonperturbative concept of "dynamical generation" is explained. A non-trivial, non-Hermitian and PT-symmetric solution for Wightman's scalar field theory in four dimensions is dynamically ...
C. Ford +25 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Generalizing Prototype Theory: A Formal Quantum Framework
Theories of natural language and concepts have been unable to model the flexibility, creativity, context-dependence, and emergence, exhibited by words, concepts and their combinations.
Diederik eAerts +3 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Is That a Real Theory or Did You Just Make It Up?
The title of this paper was derived from an incident I observed some years ago while accompanying a highly talented musician-songwriter friend to a performance.
Odis E. Simmons
doaj
Aims and Objectives: Concept maps as learning tool facilitate development of meaningful learning. It was developed by Novak and Gowin and is based on Ausubel's theory of meaningful learning.
Mahindra Kumar Anand +2 more
doaj +1 more source

