Results 241 to 250 of about 3,076,120 (383)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Severe maternal morbidity from conception to 6 weeks postpartum in Ontario: a population-based, longitudinal cohort study. [PDF]

CMAJ
Rajasingham M, Premranjith P, Brown HK, Atkinson DJ, D'Souza R, Frey BN, Green SM, Jack SM, Muraca GM, SERENE Study Investigators.   +9 more
europepmc   +1 more source

Echantillonnage direct de franges lumineuses avec des nanodétecteurs supraconducteurs dans un interféromètre en optique intégrée : application à la conception et la réalisation d'un micro-spectromètre SWIFTS

, 2011
Paul Cavalier
openalex   +1 more source

NOURI, M. Conflits, pouvoir et médiation: conceptions, trajectoires et enjeux. Éditions Universitaires Européennes, Bruxelles, 2016.

, 2017
Beatriz Molina Rueda
openalex   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Threshold-dependent effect of the neutrophil-to-albumin ratio (NAR) in early pregnancy: a novel insight for preeclampsia risk prediction. [PDF]

Am J Transl Res
Hu W, Zhang Y, Dong W, Wei R, Zhu T, Deng R, Qiao L, Zheng Q.   +7 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Family planning of infertile couples: a systematic review of intentions regarding parenthood and return to ART. [PDF]

Hum Reprod
Li Piani L, Esposito G, Reschini M, Donnez J, Parazzini F, Somigliana E.   +5 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Impact of Short-Term Estrogen Therapy on Endometrial Polyps Recurrence in Women with Intrauterine Adhesion and Endometrial Polyps: A Retrospective Cohort Study. [PDF]

Int J Womens Health
Jiang S, Yi X, Zheng M, Ouyang Y, Chen Y, Xie M, Chen S, Chen D, Zhong X.   +8 more
europepmc   +1 more source