Results 71 to 80 of about 6,265,653 (300)
Differential impact of genetic deletion of TIGIT or PD-1 on melanoma-specific T-lymphocytes
OncoImmunologyImmune checkpoint (IC) blockade and adoptive transfer of tumor-specific T-cells (ACT) are two major strategies to treat metastatic melanoma. Their combination can potentiate T-cell activation in the suppressive tumor microenvironment, but the autoimmune ...
Gwenann Cadiou +12 more
doaj +1 more source
The concept ‘indistinguishable’ [PDF]
Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics, 2020 The concept of indistinguishable particles in quantum theory is fundamental to questions of ontology. All ordinary matter is made of electrons, protons, neutrons, and photons and they are all indistinguishable particles. Yet the concept itself has proved elusive, in part because of the interpretational difficulties that afflict quantum theory quite ...
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian +7 more
wiley +1 more source
Thick Concepts and Variability [PDF]
, 2011 Some philosophers hold that so-called "thick" terms and concepts in ethics (such as 'cruel,' 'selfish,' 'courageous,' and 'generous') are contextually variable with respect to the valence (positive or negative) of the evaluations that they may be used to
Vayrynen, PP
core +2 more sources
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego +10 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
Analysis of Passenger Car Tailpipe Emissions in Different World Regions through 2050
Future TransportationThis study presents a carbon dioxide (CO2), exhaust particulate matter (PM2.5) and nitrogen oxide (NOx) tailpipe emission analysis of passenger cars in nine countries, representing different world regions up to 2050 using a bottom-up calculation method ...
Murat Senzeybek +3 more
doaj +1 more source
Concepts of spawning targets [PDF]
, 2000 This report discusses the concepts of spawning targets. Spawning target setting is based on the fact that the number of smolts produced by any given river is constrained by habitat availability.
core
Distributed Computing Concepts in D0
, 2003 The D0 experiment faces many challenges enabling access to large datasets for physicists on four continents. The new concepts for distributed large scale computing implemented in D0 aim for an optimal use of the available computing resources while ...
Wicke, Daniel
core +1 more source