Results 141 to 150 of about 145,535 (283)

A conceptual model of online information behavior in the chronic disease trajectory

, 2014
Michael Zarro, Xia Lin
openalex   +1 more source

A Conceptual Framework of the Way Forward to a Community Pharmacist–General Practitioner Collaborative Medication Therapy Management Model for Chronic Diseases in Malaysian Primary Care: A Qualitative Study

, 2021
Naeem Mubarak, Sarwat Ali Raja, Asma Sarwar Khan, Sabba Kanwal, Nasira Saif-ur-Rehman, Muhammad Majid Aziz, Irshad Hussain, Ernieda Hatah, Che Suraya Zin   +8 more
openalex   +2 more sources

A Conceptual Model of Functional Health Literacy to Improve Chronic Airway Disease Outcomes [PDF]

, 2020
Iraj Poureslami, J Mark FitzGerald, Noah Tregobov, Jessica Shum, Alizeh Akhtar, Saron Kassay, Kassandra Starnes, Austin McMillan, Maryam Mahjob   +8 more
openalex   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

A Contribution to the Conceptual Model of Occurrence of Autoimmune Diseases

In this paper, an attempt is made to shed additional light on the role of infectious agents (bacteria, viruses, etc.) in autoimmune diseases. While the correlation between them is well established, many points remain obscure. To offer a concise framework for many of the relevant research findings, the following conceptual model is discussed ...
openaire   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A conceptual health state diagram for modelling the transmission of a (re)emerging infectious respiratory disease in a human population [PDF]

Marc Avramov, Vanessa Gabriele-Rivet, Rachael M. Milwid, Victoria Ng, Nicholas H. Ogden, Valérie Hongoh   +5 more
openalex   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Mitochondrial stress as a conceptual interface between bacterial infection and post-infectious metabolic disease. [PDF]

Front Cell Infect Microbiol
Plaza N, Pérez-Reytor D, Corsini G, García K, Urrutia ÍM.   +4 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source