Results 21 to 30 of about 145,535 (283)

Development of a Conceptual Model of Disease Progression for Use in Economic Modeling of Chronic Obstructive Pulmonary Disease [PDF]

Medical Decision Making, 2016
Background. To develop and validate a new conceptual model (CM) of chronic obstructive pulmonary disease (COPD) for use in disease progression and economic modeling. The CM identifies and describes qualitative associations between disease attributes, progression and outcomes. Methods.
Maggie Tabberer, Sebastian Gonzalez‐McQuire, Hana Muellerova, Andrew Briggs, Maureen Rutten‐van Mölken, Mike Chambers, David A. Lomas   +6 more
openalex   +5 more sources

A conceptual model for healthcare-seeking research and interventions in cutaneous leishmaniasis [PDF]

International Journal for Equity in Health
Background Healthcare-seeking is not merely a biomedical response to illness but a socially and culturally embedded practice reflecting the dynamic interplay of multiple factors.
Sonali Dinushika Gunasekara, Nuwan Darshana Wickramasinghe, Kosala Gayan Weerakoon, Manoj Sanjeewa Fernando, Chandani Liyanage, Helen Philippa Price, Suneth Buddhika Agampodi, Thilini Chanchala Agampodi, Lisa Dikomitis   +8 more
doaj   +2 more sources

Systematic review and consensus conceptual model of meaningful symptoms and functional impacts in early Parkinson’s Disease [PDF]

npj Parkinson's Disease
A comprehensive, patient-centered conceptual model of early Parkinson’s is lacking and is greatly needed. A systematic review and meta-synthesis of qualitative and quantitative research was conducted by a multi-stakeholder taskforce using JBI Mixed ...
Jennifer R. Mammen, Jamie L. Adams, Rikki Mangrum, Yuge Xiao, William Barbosa, Mirinda Tyo, Christopher Redmond, Cheryl Carter, Kelly Cifelli, Robert Cifelli, Hope Maruzo, Jim Meeker, Gerry Shultz, Colbren Thomas, Claire Bale, Evan Davies, Catherine M. Kopil, Connie Marras, Tiago Mestre, Thomas Morel, Tanya Simuni, Glenn T. Stebbins, Daniel Weintraub, Diane Stephenson   +23 more
doaj   +2 more sources

Why gender and sex matter in infectious disease modelling: A conceptual framework

SSM - Population Health
The COVID-19 pandemic underscored the differential impact of infectious diseases across population groups, with gender and sex identified as important dimensions influencing transmission and health outcomes. Sex-related biological factors, such as differences in immune response and comorbidities, contribute to men's heightened severity risks, while ...
Diane Auderset, Julien Riou, Carole Clair, Matthieu Perreau, Yolanda Mueller, Joëlle Schwarz   +5 more
  +6 more sources

A conceptual model of the role of infectious agents in autoimmune diseases

Microbes & Immunity
The correlation between microbes and autoimmunity is well established, but many underlying mechanisms remain obscure. Thus, this paper attempts to elucidate the role of infectious agents (bacteria, viruses, etc.) in autoimmune diseases. To offer a concise framework for many relevant research findings, the following general conceptual model is proposed ...
Konstantinos L. Katsifarakis
openalex   +2 more sources

Chronic disease care integration into primary care services in sub-Saharan Africa: a ‘best fit’ framework synthesis and new conceptual model

Family Medicine and Community Health, 2022
Objective To examine the relevance of existing chronic care models to the integration of chronic disease care into primary care services in sub-Saharan Africa and determine whether additional context-specific model elements should be considered.Design ...
Simon R Harrison, Aileen M Jordan
doaj   +1 more source

Conceptual model for the health technology assessment of current and novel interventions in rheumatoid arthritis. [PDF]

PLoS ONE, 2018
The objective of this study was to evaluate current approaches to economic modeling in rheumatoid arthritis (RA) and propose a new conceptual model for evaluation of the cost-effectiveness of RA interventions.
Evo Alemao, Maiwenn J Al, Annelies A Boonen, Matthew D Stevenson, Suzanne M M Verstappen, Kaleb Michaud, Michael E Weinblatt, Maureen P M H Rutten-van Mölken   +7 more
doaj   +1 more source

Rationale and Criteria for a COVID-19 Model Framework

Viruses, 2021
Complex systems are inherently multilevel and multiscale systems. The infectious disease system is considered a complex system resulting from the interaction between three sub-systems (host, pathogen, and environment) organized into a hierarchical ...
Francesco Messina, Chiara Montaldo, Isabella Abbate, Manuela Antonioli, Veronica Bordoni, Giulia Matusali, Alessandra Sacchi, Emanuela Giombini, Gian Maria Fimia, Mauro Piacentini, Maria Rosaria Capobianchi, Francesco Nicola Lauria, Giuseppe Ippolito, on behalf of COVID-19 Scoping Review Working Group   +13 more
doaj   +1 more source

Conceptual Model of Lean Body Mass in Pediatric Inflammatory Bowel Disease [PDF]

Journal of Pediatric Gastroenterology and Nutrition, 2019
ABSTRACTYouth with inflammatory bowel disease (IBD) demonstrate deficits in lean mass (LM) placing them at increased risk for future health problems, including reduction of bone mass and impaired bone architecture. Research suggests that deficits in LM are multifactorial, including influences from the disease and its treatment, and health behaviors ...
Margaux J, Barnes, Mary K, Lynch, Molly D, Lisenby, Traci, Jester, Jeanine, Maclin, Taylor, Knight, Gordon, Fisher, Barbara, Gower   +7 more
openaire   +2 more sources

Development of a Conceptual Model of the Patient Experience in Small Cell Lung Cancer: A Qualitative Interview Study

Oncology and Therapy, 2023
Introduction Small cell lung cancer (SCLC) is a subtype of lung cancer, the second most common cancer diagnosis worldwide. Currently, there is little published qualitative research that provides insight into the disease-related symptoms and impacts that ...
Danielle E. Altman, Xinke Zhang, An-Chen Fu, Alissa R. Rams, Jessica A. Baldasaro, Samir Ali Ahmad, Michael Schlichting, Patrick Marquis, Elena Benincasa, Camilo Moulin, Vivek Pawar   +10 more
doaj   +1 more source