ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone+19 more
wiley +1 more source
Land in balance: The scientific conceptual framework for Land Degradation Neutrality
A. Cowie+12 more
semanticscholar +1 more source
Identifying key components of a global conceptual framework for adolescent nutrition: Review, nominal group technique and youth co-design. [PDF]
Estecha-Querol S+13 more
europepmc +1 more source
ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos+11 more
wiley +1 more source
Correction to: Continuous education in sexology: the International Online Sexology Supervisors (IOSS) conceptual framework and roadmap. [PDF]
europepmc +1 more source
An Introduction to the Artificial Intelligence-Driven Technology Adoption in Nursing Education Conceptual Framework: A Mixed-Methods Study. [PDF]
Maguire MB, White A.
europepmc +1 more source
ABSTRACT Objective SCN1A‐related seizures first present as febrile seizures (FS). Definitive features emerge later, making early diagnosis challenging. We evaluated the diagnostic yield and clinical characteristics of pathogenic SCN1A variants in FS, and analyzed the effect of variant characteristics on clinical phenotypes required for early ...
Jia Wang+11 more
wiley +1 more source
Work contributions to the family: Developing a conceptual and research framework
Jacqueline J. Goodnow+1 more
openalex +1 more source
A Conceptual Framework for Empowerment of Psychiatric Nurses Caring for Children with Mental Health Challenges. [PDF]
Machailo RM, Koen MP, Matsipane MJ.
europepmc +1 more source
Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD
ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo+14 more
wiley +1 more source