Results 41 to 50 of about 4,808,194 (314)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
5G Enabled Freeports: A Conceptual Framework
IEEE Access, 2022 A novel conceptual framework is developed that depicts a generic Freeport model underpinned by 5G technology. The framework is based on preliminary findings from a 5G testbed project and secondary 5G use cases from both practice and academic literature ...
Yingli Wang +5 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
International Journal of Endorsing Health Science Research, 2018 Background: Verbal Autopsy/Social Autopsy (VASA) tools should be based on a well-holistic conceptual framework, allowing them to record and organize a wide range of determinants and contributors of child mortality in developing countries. This paper aims
Muhammad Bilal Siddiqui +2 more
doaj +1 more source
A Conceptual Framework for Personal Science
Frontiers in Computer Science, 2020 This paper introduces a conceptual framework to guide research and education into the practice of personal science, which we define as using empirical methods to pursue personal health questions. Personal science consists of five activities: questioning,
Gary Isaac Wolf, Martijn De Groot
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The Distinctions Between Theory, Theoretical Framework, and Conceptual Framework
Academic medicine : journal of the Association of American Medical Colleges, 2019 Health professions education (HPE) researchers are regularly asked to articulate their use of theory, theoretical frameworks, and conceptual frameworks in their research.
L. Varpio +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Learner Engagement in Blended Learning Environments: A Conceptual Framework
Online Learning, 2019 Learner engagement correlates with important educational outcomes, including academic achievement and satisfaction. Although research is already exploring learner engagement in blended contexts, no theoretical framework guides inquiry or practice, and ...
Lisa R. Halverson, Charles R. Graham
semanticscholar +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Constructing a conceptual framework for psychosocial nursing
نشریه پرستاری ایران, 1993 Increasing complexity of treatment and current psychological health problems reveals the importance of uniqueness psychological health care in the nursing profession .
MM BaniAsad
doaj