Results 61 to 70 of about 4,808,194 (314)

Building a Conceptual Framework: Philosophy, Definitions, and Procedure

open access: yesInternational Journal of Qualitative Methods, 2009
In this paper the author proposes a new qualitative method for building conceptual frameworks for phenomena that are linked to multidisciplinary bodies of knowledge.
Yosef Jabareen
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Algemene beginselen en het Conceptual Framework [PDF]

open access: yesMAB, 2016
In Titel 9 en de EU Accounting Directive zijn diverse algemene beginselen opgenomen. In het Conceptual Framework (CF) van de International Accounting Standards Board (IASB) zijn kwalitatieve kenmerken van nuttige informatie geformuleerd. Dit artikel gaat
Martin Hoogendoorn
doaj   +3 more sources

Conceptual Framework for Product Service Systems

open access: yesSystems, 2018
To remain competitive in the current market, an enterprise must differentiate itself based on higher value propositions. For this purpose, since improving the product or service performance can reach some limits, one potential solution is to move towards
Amir Pirayesh   +9 more
doaj   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

open access: yesFEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos   +3 more
wiley   +1 more source

Knowledge Governance: Building a Conceptual Framework

open access: yesFronteiras: Journal of Social, Technological and Environmental Science, 2019
This exploratory systematic literature review is a starting point for a deep literature review on “Knowledge Governance” (KGOV) topic. The aim is to have a quick picture about KGOV; specifically trying to identify the seminal, core and relevant documents.
Isabel Pinho   +2 more
doaj   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Conceptual Framework

open access: yesVisions in Leisure and Business, 2022
Derrick Manns, Bob Lee, David Groves
doaj   +1 more source

A Conceptual Framework for Examining Trust towards Zakat Institution

open access: yesInternational Journal of Economics and Financial Issues, 2016
This paper aims to propose a research conceptual framework for examining trust towards zakat institution amongst Moslem business owners. An extensive literature review method was utilized to identify and analyze the relevant literatures in order to ...
Mohamad Zulkurnai Ghazali   +2 more
doaj  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

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