Results 71 to 80 of about 268,314 (271)

Postdigital augmented spaces: A conceptual framework

open access: yesVLC Arquitectura
Contemporary augmented spaces are situated in-between digital-analog, material-immaterial, online-offline, and real-virtual binaries. Relatedly, postdigital as a concept suggests that digital technologies are now integrated with almost all aspects of the
Sıla Burcu Başarır, Yüksel Demir
doaj   +1 more source

Towards a Conceptual Framework for WikiGIS

open access: yesFuture Internet, 2014
As an emerging complex concept, GeoDesign requires an innovative theoretical basis, tools, supports and practices. For this reason, we propose a new concept, “WikiGIS”, designed to answer some dimensions of the GeoDesign process.
Wided Batita   +3 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Common controls driven conceptual leadership framework

open access: yesFinnish Journal of eHealth and eWelfare, 2018
The forthcoming social welfare and healthcare reform in Finland with its organizational, financing and steering changes challenges the leadership. All service systems levels of the social welfare and healthcare have to achieve performance objectives ...
Petteri Mussalo   +6 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Modeling Conceptual Framework for Implementing Barriers of AI in Public Healthcare for Improving Operational Excellence: Experiences from Developing Countries [PDF]

open access: gold, 2022
S. K. Joshi   +6 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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