Results 91 to 100 of about 3,563,997 (305)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Climate obstruction and nationalism: a conceptual map

Frontiers in Political Science
Nationalism is notoriously an ideology that can fit opposite ideological and political necessities. Since 2020, an emerging literature exploring nationalism’s connections with climate change has developed. Yet, nationalism’s role in the decisive practice
Daniele Conversi, Lorenzo Posocco, Haro L. Karkour, Piotr Żuk, Jürgen Scheffran, Kjell Vowles, Virginie Arantes, Yogi Hale Hendlin, Joan Enguer   +8 more
doaj   +1 more source

Moluccan Islands 1:125,000 [cartographic material] /

, 1943
1st ed. - AMS 1. Relief shown by hachures, spot sheights, and contours.; "Work Projects Administration Project, O.P. 165-200-3"; Standard map series designation: [Series] A.M.S.
United States. Army Map Service. Indianapolis Unit.
core  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

China proper SE 1:250,000 [cartographic material] /

, 1944
Map series of the southeastern corner of China showing international, province and district boundaries, transportation, water features, walls, rice fields and populated places.
United States. Army Map Service.
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Southeast Asia road map [cartographic material] /

, 1961
Various eds. Road map series of South East Asia showing international and administrative boundaries, transportation, water features, vegetation and populated places.
United States. Army Map Service.
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Asia transportation map 1:2 000 000 [cartographic material] : Burma /

, 1945
Edition 2-AMS. Map of Burma showing international boundaries, transportation, water features and populated places.; Standard map series designation: Series 5201.; Also available online http://nla.gov.au/nla.map-vn676361.Series ...
United States. Army Map Service.
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source