Results 221 to 230 of about 16,017,577 (292)

Development of a conceptual model of intertemporal decision-making ability for young and middle-aged stroke patients within physical activity: a qualitative study. [PDF]

Front Psychol
Li X, Zhang C, Liu Y, Zhou P.
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

A General Predictive and Conceptual Model for Repulsive Electronic States in Valence Ionized Molecules. [PDF]

J Chem Theory Comput
Dockx L, Sztáray B, Dutoi AD.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Feel the Rhythm: a co-constructed conceptual model of freezing of gait based on the lived experience of people with Parkinson’s

Young W, Kal E, Ellmers T, Maslivec A, Wilson M, Russo Y, Evans K, Norris M.   +7 more
europepmc   +1 more source

Applying the Target Study Conceptual Model to Measure Racial and Ethnic Disparities in Hypertension Treatment Intensification. [PDF]

Epidemiology
Meche A, Boonyasai RT, Hsu YJ, Greer RC, Mehta HB, Alexander GC, Segal JB, Cooper LA, Jackson JW.   +8 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

We are still in it: a conceptual model for moral injury and burnout in alternative response programs to guide intervention. [PDF]

Front Psychiatry
Worthen M, De Bourbon S, Breedlove O, Ewing C, Graterol J, Harmon A, Hines N, Lundgren E, Mason M, Marchiselli M, Mendoza V, Nguyen K, Rubin B, Sloan A, Maguen S.   +14 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Robots, ledgers, and RevPAR: a blockchain-enabled AI-robotics conceptual model for sustainable hotel revenue and asset management. [PDF]

Front Robot AI
Jackson LA.
europepmc   +1 more source