Results 121 to 130 of about 21,646,523 (374)
The notion of role in conceptual modeling
Dates de conf{\'e}rence : octobre 1997 ...
Reynaud, Chantal+3 more
openaire +4 more sources
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
A Conceptual Model for Scholarly Research Activity [PDF]
This paper presents a conceptual model for scholarly research activity, developed as part of the conceptual modelling work within the ???Preparing DARIAH??? European e-Infrastructures project.
Benardou, Agiatis+3 more
core
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Closure to “Fitting Methods for Conceptual Catchment Models” [PDF]
Richard P. Ibbitt, Terence O’Donnell
openalex +1 more source
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Conceptual modelling: choosing a critical infrastructure modelling methodology [PDF]
This paper reports on further research undertaken regarding systems modelling as applied to critical infrastructure systems and networks and builds upon the initial modelling research of Pye and Warren (2006a).
Pye, Graeme, Warren, Matthew
core +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Elevated Mixed Layers in the Regional Severe Storm Environment: Conceptual Model and Case Studies [PDF]
Toby N. Carlson+3 more
openalex +1 more source
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source