Results 141 to 150 of about 21,646,523 (374)
Molecular Oncology, EarlyView.Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Cognitive and affective motivation in conceptual modelling
Revista Colombiana de Computación, 2002 A proposal is presented towards the extension of conceptual models of information systems, in order to allow specification and simulation of the behaviour of agents with an adequate degree of realism.
Antonio L. Furtado +1 more
doaj
Relativism and views in a conceptual data base model [PDF]
, 1980 Peter Kreps
openalex +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
A conceptual model of a single-event gate-rupture in power MOSFETs [PDF]
, 1993 J.R. Brews +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Nonconventional Technologies Review, 2019 The conceptual design stage involves a compound set of objectives and constraints such as issues of function, aesthetic and ergonomics. Furthermore, computational design methodologies offer a great number of advantages for engineering and manufacturing ...
Panagiotis Kyratsis +3 more
doaj
A conceptual model of solute acquisition by Alpine glacial meltwaters [PDF]
, 1993 Martyn Tranter +4 more
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