Results 161 to 170 of about 21,646,523 (374)

Best practices for conceptual modelling in environmental planning and management

Environmental Modelling & Software, 2016
R. Argent, R. Sojda, C. Giupponi, B. McIntosh, A. Voinov, H. Maier   +5 more
semanticscholar   +1 more source

Conceptual Modelling of Services

, 2012
Conceptual Modelling of ...
Ma, Hui, Schewe, Klaus-Dieter, Thalheim, Bernhard, Wang, Qing (Ms)   +3 more
openaire   +2 more sources

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Complexity measures for object-oriented conceptual models of an application domain. [PDF]

According to Norman Fenton few work has been done on measuring the complexity of the problems underlying software development. Nonetheless, it is believed that this attribute has a significant impact on software quality and development effort.
Dedene, Guido, Poels, Geert
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Application of deterministic conceptual model for water balance studies

, 1980
S. D. S. ABBI, A. K. Gosain, PANKAJA NARAYANAN   +2 more
openalex   +2 more sources

PubFAIR Conceptual Model

, 2019
This presentation was made at the COAR 2019 Annual Meeting & General Assembly, Lyon (France)
openaire   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

A conceptual model of water transport through unsaturated soil zone

, 1980
P. S. Datta, S. K. Gupta, Sanjay Sharma
openalex   +2 more sources

Object interaction in object-oriented deductive conceptual models [PDF]

, 1993
Carme Quer, Antoni Olivé
openalex   +1 more source