Results 181 to 190 of about 21,646,523 (374)
Supporting conceptual design based on the function-behavior-state modeler [PDF]
Yasushi Umeda+4 more
openalex +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
As reflexões desse artigo concentram-se no âmbito da modelagem conceitual com foco na análise faceta, teoria esta que defende o agrupamento de termos de um dado campo do conhecimento em facetas homogêneas e mutuamente exclusivas, derivadas de suas ...
Elizabeth Andrade Duarte+1 more
doaj
Conceptual models and cognitive learning styles in teaching recursion [PDF]
Cheng-Chih Wu+2 more
openalex +3 more sources
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Beta-blockade in the management of chronic heart failure: Another step in the conceptual evolution of a neurohormonal model of the disease [PDF]
Milton Packer
openalex +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
An economic approach to collective management of endemic animal diseases [PDF]
The control of animal diseases is an issue of particular interest in animal production chains. Because of their direct impact on production, animal diseases generate income shortfalls for farmers.
Krebs, Stephane, Rat-Aspert, Olivier
core +1 more source
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren+8 more
wiley +1 more source